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Literature summary for 5.3.1.24 extracted from

  • Potts, J.M.; Drapeau, G.R.
    Partial characterization of phosphoribosyl transferase, phosphoribosyl anthranilate isomerase, and indole glycerol phosphate synthase from Serratia marcescens (1972), J. Bacteriol., 111, 334-339.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.1.24

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 indole-3-glycerol-phosphate synthetase/PRA isomerase complex, gel filtration Serratia marcescens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-(5-phospho-beta-D-ribosyl)anthranilate Serratia marcescens involved in tryptophan biosynthesis from chorismate 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?
N-(5-phospho-beta-D-ribosyl)anthranilate Serratia marcescens HY involved in tryptophan biosynthesis from chorismate 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-
Serratia marcescens
-
 bifunctional indole-3-glycerol-phosphate synthetase/PRA isomerase complex
-
Serratia marcescens HY
-
-
-

Purification (Commentary)

Purification (Comment) Organism
indole-3-glycerol-phosphate synthetase/PRA isomerase complex, 70fold Serratia marcescens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.5
-
 37°C, indole-3-glycerol-phosphate synthetase/PRA isomerase complex Serratia marcescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-(5-phospho-beta-D-ribosyl)anthranilate
-
 Serratia marcescens 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?
N-(5-phospho-beta-D-ribosyl)anthranilate involved in tryptophan biosynthesis from chorismate Serratia marcescens 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?
N-(5-phospho-beta-D-ribosyl)anthranilate
-
 Serratia marcescens HY 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?
N-(5-phospho-beta-D-ribosyl)anthranilate involved in tryptophan biosynthesis from chorismate Serratia marcescens HY 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 48000, indole-3-glycerol-phosphate synthetase/PRA isomerase complex, SDS-PAGE Serratia marcescens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Serratia marcescens