Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclosporin A | and cyclosporin derivative with modifications in the D-Ser side chain. Inhibition leads to failure of polymerization of the extracellular multi-domain protein hensin, plus the loss of the apical cytoskeleton, apical microvilli, and the columnar epithelial shape of clone C cells | Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Oryctolagus cuniculus | cyclophilin A mediates the polymerization and matrix assembly of hensin, a multifunctional, multi-domain protein implicated in the regulation of epithelial differentiation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | Q9TTC6 | isoform cyclophilin A | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cyclophilin A mediates the polymerization and matrix assembly of hensin, a multifunctional, multi-domain protein implicated in the regulation of epithelial differentiation | Oryctolagus cuniculus | ? | - |
? |