Literature summary for 5.2.1.8 extracted from

Shimizu, T.; Akiyama, H.; Abe, Y.; Sasada, H.; Sato, E.; Miyamoto, A.; Uchida, T.
Expression of Pin1, a peptidyl-prolyl isomerase, in the ovaries of eCG/hCG-treated immature female mice (2006), J. Reprod. Dev., 52, 287-291.

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Activating Compound

Activating Compound	Comment	Organism	Structure
equine chorionic gonadotropin	significant increase in expression of isoform Pin1 mRNA, application of human chorionic gonadotropin attenuates this increase. mRNA expression of E2F transcription factor, which controls the expression of Pin1, is decreased in the ovaries after treatment with equine chorionic gonadotropin. Protein level of Pin1 shows the same tendencies as the expression of RNA	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q9QUR7	immature female mice, isoform Pin1	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovary	of mice treated with equine or human chorionic gonadotropin, eCG or hCG, resp.	Mus musculus	-

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Release 2023.1 (January 2023)