Cloned (Comment) | Organism |
---|---|
- |
Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FK506 | 50% inhibition at 0.00032 mM | Plasmodium falciparum | |
additional information | cyclosporin A is not inhibitory up to 0.005 mM | Plasmodium falciparum | |
Rapamycin | 50% inhibition at 0.00048 mM | Plasmodium falciparum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34800 | - |
x * 34800, calculated | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Plasmodium falciparum | enzyme inhibits the phosphatase activity of calcineurin independently of FK506 binding. Enzyme also inhibits thermal aggregation of two model substrates indicating chaperone proterties | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme inhibits the phosphatase activity of calcineurin independently of FK506 binding. Enzyme also inhibits thermal aggregation of two model substrates indicating chaperone proterties | Plasmodium falciparum | ? | - |
? | |
succinyl-Ala-Leu-(cis)-Pro-Phe-p-nitroanilide | - |
Plasmodium falciparum | succinyl-Ala-Leu-(trans)-Pro-Phe-p-nitroanilide | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 34800, calculated | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
FKBP35 | - |
Plasmodium falciparum |