Literature summary for 5.2.1.8 extracted from

Breiman, A.; Fawcett, T.W.; Ghirardi, M.L.; Mattoo, A.K.
Plant organelles contain distinct peptidylprolyl cis,trans-isomerases (1992), J. Biol. Chem., 267, 21293-21296.

Search for more literature for 5.2.1.8

Inhibitors

Inhibitors	Comment	Organism	Structure
cyclosporin A	inhibits the activity largely localized to the mitochondrial matrix	Pisum sativum
Rapamycin	inhibits the activity associated with the mitochondrial membranes	Pisum sativum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
chloroplast	cyclosporin A-sensitive activity in the chloroplast is mostly localized to the thylakoids, activity associated with the chloroplast stroma and the thylakoids is not inhibited by rapamycin	Pisum sativum	9507	-
cytosol	-	Pisum sativum	5829	-
mitochondrion	cyclosporin A-sensitive activity is largely localized to the mitochondrial matrix. Rapamycin-sensitive activity is associated with the mitochondrial membranes	Pisum sativum	5739	-
additional information	presence of distinct classes of peptidyl cis,trans-isomerases in the mitochondria and the chloroplast of plants	Pisum sativum	-	-

Organism

Organism	UniProt	Comment	Textmining
Pisum sativum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-succinyl-Ala-Ala-(trans)-Pro-Phe-4-nitroanilide	-	Pisum sativum	N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide	-	?

Synonyms

Synonyms	Comment	Organism
peptidylprolyl cis,trans-isomerase	-	Pisum sativum
PPIase	-	Pisum sativum

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Release 2023.1 (January 2023)