Literature summary for 5.2.1.8 extracted from

Kofron, J.L.; Kuzmic, P.; Kishore, V.; Gemmecker, G.; Fesik, S.W.; Rich, D.H.
Lithium chloride pertubation of cis-trans peptide bond equilibria: effect on conformational equilibria in cyclosporin A and on time-dependent inhibition of cyclophilin (1992), J. Am. Chem. Soc., 114, 2670-2675.

No PubMed abstract available

Inhibitors

Inhibitors	Comment	Organism	Structure
cyclosporin A	the sequence MeLeu9-trans-MeLeu10-MeVal is responsible for the efficient binding in the active site of cyclophilin. The cis-conformer is inactive as inhibitor	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)