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Literature summary for 5.2.1.8 extracted from

  • Zeng, B.; MacDonald, J.R.; Bann, J.G.; Beck, K.; Gambee, J.E.; Boswell, B.A.
    Chicken FK506-binding protein, FKBP65, a member of the FKBP family of peptidylprolyl cis-trans isomerases, is only partially inhibited by FK506 (1998), Biochem. J., 330, 109-114.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.2.1.8

Inhibitors

Inhibitors Comment Organism Structure
cyclosporin A
-
 Gallus gallus
FK506 only one of the 4 domains can be inhibited by the immunosuppressive drug Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum rough Gallus gallus 5783
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
 x * 68000, SDS-PAGE under reducing conditions and under nonreducing conditions Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information catalyzes the refolding of type III collagen Gallus gallus ?
-
 ?
succinyl-Ala-Ala-(cis)-Pro-Phe 4-methylcoumarin 7-amide
-
 Gallus gallus succinyl-Ala-Ala-(trans)-Pro-Phe + 7-amino-4-methylcoumarin
-
 ?
succinyl-Ala-Ala-Pro-Phe 4-nitroanilide
-
 Gallus gallus succinyl-Ala-Ala-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Gln-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Gln-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Glu-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Glu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Gly-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Gly-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-His-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-His-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Lys-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Lys-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Phe-(cis)-Pro-Phe 4-nitroanilide
-
 Gallus gallus Succinyl-Ala-Phe-(trans)-Pro-Phe 4-nitroanilide
-
 ?

Subunits

Subunits Comment Organism
monomer x * 68000, SDS-PAGE under reducing conditions and under nonreducing conditions Gallus gallus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Gallus gallus