Application | Comment | Organism |
---|---|---|
diagnostics | combined AMACR/p53 analysis to identify dysplasia in inflammatory bowel disease like ulcerative colitis and Crohns disease | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon epithelium | patients with chronic inflammatory disease prostate carcinoma | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
alpha-methylacyl-CoA racemase | - |
Homo sapiens |
AMACR | - |
Homo sapiens |
P504S | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | coexpression of alpha-methylacyl coenzyme A racemase and nuclear p53 in neoplastic lesions | additional information |
Homo sapiens | positive AMACR immunehistochemistry staining is strongly associated with neoplastic transformation of the colon epithelium, AMACR positively is observed in the majority of invasive cancers and histologically recognized dysplasias | up |
General Information | Comment | Organism |
---|---|---|
malfunction | alpha-methylacyl coenzyme A racemase is positive in most cancers and dysplasias but only rarely in nonneoplastic epithelium | Homo sapiens |