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Literature summary for 5.1.99.4 extracted from

  • Guzman, G.; Wu, S.J.; Kajdacsy-Balla, A.; Cotler, S.J.
    alpha-Methylacyl-CoA racemase (AMACR/P504S) can distinguish hepatocellular carcinoma and dysplastic hepatocytes from benign nondysplastic hepatocytes (2006), Appl. Immunohistochem. Mol. Morphol., 14, 411-416.
    View publication on PubMed

Application

Application Comment Organism
diagnostics the enzyme is useful for detection of malignancies including hepatocellular carcinoma Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm diffuse cytoplasmic distribution dependent on the liver tissue type, overview Homo sapiens 5737
-
cytoplasmic vesicle coarsely granular distribution dependent on the liver tissue type, overview Homo sapiens 31410
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme can distinguish hepatocellular carcinoma and dysplastic hepatocytes from benign nondysplastic hepatocytes, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocellular carcinoma cell immunohistochemic detection and expression analysis, pattern and distribution, overview Homo sapiens
-
liver nonysplastic liver tissue, immunohistochemic detection and expression analysis, pattern and distribution, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme can distinguish hepatocellular carcinoma and dysplastic hepatocytes from benign nondysplastic hepatocytes, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase
-
Homo sapiens
AMACR
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Homo sapiens
P504S
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Homo sapiens