Literature summary for 5.1.99.1 extracted from

Chandler, R.J.; Aswani, V.; Tsai, M.S.; Falk, M.; Wehrli, N.; Stabler, S.; Allen, R.; Sedensky, M.; Kazazian, H.H.; Venditti, C.P.
Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism (2006), Mol. Genet. Metab., 89, 64-73.

Search for more literature for 5.1.99.1

Application

Application	Comment	Organism
medicine	as model to study human methylmalonic aciduria, deletion of the mce gene results in a 80% decreased incorporation of propionate into macromolecules and induces an accumulation of methylmalonic acid	Caenorhabditis elegans

Cloned(Commentary)

Cloned (Comment)	Organism
in a RNAi vector in Escherichia coli	Caenorhabditis elegans

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Caenorhabditis elegans	5739	-

Organism

Organism	UniProt	Comment	Textmining
Caenorhabditis elegans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(R)-methylmalonyl-CoA	-	Caenorhabditis elegans	(S)-methylmalonyl-CoA	-	?

Synonyms

Synonyms	Comment	Organism
MCE-1	-	Caenorhabditis elegans
MCEE	-	Caenorhabditis elegans
methylmalonyl-CoA 2-epimerase	-	Caenorhabditis elegans
methylmalonyl-CoA epimerase	-	Caenorhabditis elegans

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)