Cloned (Comment) | Organism |
---|---|
- |
Azotobacter vinelandii |
Protein Variants | Comment | Organism |
---|---|---|
D152G | mutation eliminates almost all of both the lyase and epimerase activities | Azotobacter vinelandii |
additional information | a truncated form of isoform AlgE1 (AlgE1-1) is converted to a combined epimerase and lyase by replacing the 5'-798 base pairs in the algE1-1 gene with the corresponding A-module-encoding DNA sequence from algE7 | Azotobacter vinelandii |
additional information | a truncated form of isoform AlgE1 (AlgE1-1) is converted to a combined epimerase and lyase by replacing the 5'-798 base pairs in the algE1-1 gene with the corresponding A-module-encoding DNA sequence from bifunctional isoform algE7 | Azotobacter vinelandii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Azotobacter vinelandii | Q44494 | - |
- |
Azotobacter vinelandii | Q9ZFG9 | bifunctional mannuronan C-5-epimerase and alginate lyase, reaction of EC 4.2.2.3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | isoform AlgE7 degrades M-rich alginates and a relatively G-rich alginate from the brown algae Macrocystis pyrifera most effectively, producing oligomers of 4 (mannuronan) to 7 units. The sequences cleaved are mainly G-MM and/or G-GM. G-moieties dominate at the reducing ends even when mannuronan is used as substrate, so the AlgE7 lyase/epimerase probably stimulates the lyase pathway, indicating a complex interplay between the two activities | Azotobacter vinelandii | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AlgE1 | - |
Azotobacter vinelandii |
AlgE7 | - |
Azotobacter vinelandii |