General Stability | Organism |
---|---|
DTT protects against inactivation at 4 C | Rattus norvegicus |
UDP and UDP-N-acetylglucosamine protect the enzyme from inactivation by aging | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CMP-N-acetylneuraminic acid | 50% inhibition by 0.025 mM | Rattus norvegicus | |
UDP | competitive | Rattus norvegicus | |
UDPglucose | - |
Rattus norvegicus | |
UMP | - |
Rattus norvegicus | |
UTP | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.08 | - |
UDP-N-acetyl-D-glucosamine | and a second Km-value of 0.29 mM | Rattus norvegicus | |
0.29 | - |
UDP-N-acetyl-D-glucosamine | and a second Km-value of 0.08 mM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
4°C, in presence of 0.1 mM UDP and 1 mM DTT, 3 days, 20% loss of activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine | - |
Rattus norvegicus | UDP-N-acetyl-D-mannosamine | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 8.5 | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
CMP-N-acetylneuraminic acid | - |
Rattus norvegicus |