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Literature summary for 5.1.1.5 extracted from

  • Guengerich, F.P.; Broquist, H.P.
    Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. II. The origin of pipecolic acid (1973), Biochemistry, 12, 4270-4274.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
hydroxylamine
-
Slafractonia leguminicola

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Slafractonia leguminicola L-Lys gives rise to L-pipecolate that is utilized in the biosynthesis of the piperidine alkaloids 1-acetoxy-6-aminooctahydroindolizine and 3,4,5-trihydroxyoctahydro-1-pyridine. D-Lys is converted to D-N6-acetyllysine prior to further catabolism ?
-
?

Organism

Organism UniProt Comment Textmining
Slafractonia leguminicola
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Lys
-
Slafractonia leguminicola D-Lys
-
?
additional information L-Lys gives rise to L-pipecolate that is utilized in the biosynthesis of the piperidine alkaloids 1-acetoxy-6-aminooctahydroindolizine and 3,4,5-trihydroxyoctahydro-1-pyridine. D-Lys is converted to D-N6-acetyllysine prior to further catabolism Slafractonia leguminicola ?
-
?