Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(R,S)-1-hydroxy-1-oxo-4-amino-4-carboxyphosphorinane | - |
Enterococcus faecalis | |
(R,S)-4-amino-4-carboxy-1,1-dioxotetrahydro-thiopyran | - |
Enterococcus faecalis | |
1,1-dioxo-tetrahydrothiopyran-4-one | - |
Enterococcus faecalis | |
1-hydroxyphosphinan-4-one 1-oxide | - |
Enterococcus faecalis | |
2-amino-4-phosphonobutanoic acid | - |
Enterococcus faecalis | |
bis(2-carboxyethyl)-phosphinic acid | - |
Enterococcus faecalis | |
additional information | substrate-product analogue inhibitor synthesis and evaluation, overview | Enterococcus faecalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate | Enterococcus faecalis | - |
D-glutamate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus faecalis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate | - |
Enterococcus faecalis | D-glutamate | - |
r |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
3.1 | - |
(R,S)-1-hydroxy-1-oxo-4-amino-4-carboxyphosphorinane | pH and temperature not specified in the publication | Enterococcus faecalis | |
18.4 | - |
1,1-dioxo-tetrahydrothiopyran-4-one | pH and temperature not specified in the publication | Enterococcus faecalis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
21.2 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | 1,1-dioxo-tetrahydrothiopyran-4-one | |
24.1 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | (R,S)-1-hydroxy-1-oxo-4-amino-4-carboxyphosphorinane | |
47.7 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | 1-hydroxyphosphinan-4-one 1-oxide | |
60.4 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | bis(2-carboxyethyl)-phosphinic acid | |
105 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | 2-amino-4-phosphonobutanoic acid | |
215 | - |
pH and temperature not specified in the publication | Enterococcus faecalis | (R,S)-4-amino-4-carboxy-1,1-dioxotetrahydro-thiopyran |
General Information | Comment | Organism |
---|---|---|
physiological function | D-glutamate is an essential biosynthetic building block of the peptidoglycans that encapsulate the bacterial cell wall | Enterococcus faecalis |