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Literature summary for 5.1.1.18 extracted from
- Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase (2008), J. Pharmacol. Sci., 107, 270-276.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| morphine | chronic administration significantly augments both serine racemase mRNA and protein expression in all brain regions and leads to slight but significant elevation in the concentration of D-serine in the cortex, striatum, and hippocampus | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q76EQ0 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| brain cortex | - |
Rattus norvegicus | - |
| hippocampus | - |
Rattus norvegicus | - |
| striatum | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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