Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | activates, activation mechanism, overview | Mus musculus | |
ATP | activates, activation mechanism, overview, synergistic with Ca2+ | Mus musculus | |
glutamate receptor interacting protein | i.e. GRIP, a multi-PSD-95/discs large/ZO-1 domain protein, that is usually coupled to the GluR2/3 subunits of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid Ca2+ channel, in vivo activation by full-length GRIP, determination of required length and domains of the protein for activation, activation mechanism, overview | Mus musculus | |
additional information | activation of serine racemase by divalent cations has been assumed to be a side-effect associated with ATP binding, activation mechanisms and ligand binding, molecular modelling with the human enzyme, overview | Mus musculus |
Cloned (Comment) | Organism |
---|---|
expression of untagged and of N-terminally His6-tagged and C-terminally FLAG-tagged enzyme in COS-7 cells, co-expression with glutamate receptor interacting protein or FLAG-tagged glutamate receptor interacting protein domain PDZ6 | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates, activation mechanism, overview, synergistic ATP binding | Mus musculus | |
Mg2+ | actvates, activation mechanism, overview, synergistic ATP binding | Mus musculus | |
additional information | activation of serine racemase by divalent cations has been assumed to be a side-effect associated with ATP binding, activation mechanisms and ligand binding, molecular modelling with the human enzyme, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-serine | Mus musculus | - |
D-serine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-serine | - |
Mus musculus | D-serine | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.1 | - |
assay at | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | prosthetic group | Mus musculus |