Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Co2+ | - |
Mus musculus | |
Cu2+ | - |
Mus musculus | |
EDTA | - |
Mus musculus | |
Fe2+ | slight inhibition of both activities | Mus musculus | |
Ni2+ | slight inhibition of both activities | Mus musculus | |
Zn2+ | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
30 | - |
L-serine | pH 8.0, 37°C, racemization reaction | Mus musculus | |
49 | - |
D-serine | pH 8.0, 37°C, racemization reaction | Mus musculus | |
75 | - |
L-serine | pH 8.0, 37°C, elimination reaction | Mus musculus | |
75 | - |
D-serine | pH 8.0, 37°C, elimination reaction | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Mus musculus | |
Mg2+ | required, both activities | Mus musculus | |
Mn2+ | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
2 * 37000, SDS-PAGE | Mus musculus |
78000 | - |
gel filtration | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9QZX7 | bifunctional enzyme, racemization of serine and elimination of L-serine and L-serine-O-sulfate to form pyruvate | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme expressed in insect cells | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-serine | - |
Mus musculus | pyruvate + NH3 | - |
? | |
D-serine | - |
Mus musculus | L-serine | - |
r | |
L-serine | - |
Mus musculus | pyruvate + NH3 | - |
? | |
L-serine | - |
Mus musculus | D-serine | - |
r |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 37000, SDS-PAGE | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 9.5 | - |
Mus musculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
negligible activity below | Mus musculus |