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Literature summary for 5.1.1.13 extracted from

  • Matsuda, S.; Katane, M.; Maeda, K.; Kaneko, Y.; Saitoh, Y.; Miyamoto, T.; Sekine, M.; Homma, H.
    Biosynthesis of D-aspartate in mammals the rat and human homologs of mouse aspartate racemase are not responsible for the biosynthesis of D-aspartate (2015), Amino Acids, 47, 975-985 .
    View publication on PubMed
Search for more literature for 5.1.1.13

Cloned(Commentary)

Cloned (Comment) Organism
gene Got1l1, real-time PCR expression analysis Homo sapiens
gene Got1l1, real-time PCR expression analysis, relationships between the D-Asp content and expression levels of Got1l1 and Ddo mRNAs in cultured rat cells Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
additional information knockdown of Got1l1 in cultured GH3 cells Rattus norvegicus
additional information knockdown of Got1l1 in HeLa cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-
cytoplasm
-
 Rattus norvegicus 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
GH3 cell
-
 Rattus norvegicus
-
HeLa cell
-
 Homo sapiens
-
pituitary gland cell line
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the aspartate aminotransferase, UniProt ID Q8NHS2, EC 2.6.1, exhibits low aspartate racemase activity in contrast to the murine enzyme GOT1L1 Homo sapiens ?
-
 ?
additional information the glutamic-oxaloacetic transaminase 1-like 1, UniProt ID A0A0U1RVK4, exhibits low aspartate racemase activity in contrast to the murine enzyme GOT1L1 Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
GOT1L1
-
 Homo sapiens
GOT1L1
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Homo sapiens
pyridoxal 5'-phosphate
-
 Rattus norvegicus

General Information

General Information Comment Organism
malfunction knockdown of Got1l1 does not reduce the total D-Asp content of the cells and their culture medium Homo sapiens
malfunction knockdown of Got1l1 does not reduce the total D-Asp content of the cells and their culture medium Rattus norvegicus
physiological function enzyme GOT1L1 contributes little, if at all, to the biosynthesis of D-Asp in human cells, relationships between the D-Asp content and expression levels of Got1l1 and Ddo mRNAs in cultured human cells Homo sapiens
physiological function enzyme GOT1L1 contributes little, if at all, to the biosynthesis of D-Asp in rat cells, relationships between the D-Asp content and expression levels of Got1l1 and Ddo mRNAs in cultured rat cells, overview Rattus norvegicus