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Literature summary for 5.1.1.13 extracted from

  • Topo, E.; Soricelli, A.; DAniello, A.; Ronsini, S.; DAniello, G.
    The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats (2009), Reprod. Biol. Endocrinol., 7, 120-130.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate Rattus norvegicus
-
 D-aspartate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
pituitary gland
-
 Rattus norvegicus
-
serum
-
 Rattus norvegicus
-
testis
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 the pituitary gland is the tissue which contains the highest enzymatic activity, with 20.0 EU/mg protein, followed by: testis; brain, liver, kidney and serum, 1 enzyme unit (EU) is defined as the amount of the enzyme capable of generating 1 nmol of D-Asp in 60 min of incubation at 37°C and in the assay conditions (0.1 M Tris-HCl,10 mM EDTA, 0.1 M sodium L-aspartate) Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate
-
 Rattus norvegicus D-aspartate
-
 ?

Synonyms

Synonyms Comment Organism
D-Asp racemase
-
 Rattus norvegicus
D-Aspartate racemase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Rattus norvegicus