Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-cycloserine | an alanine racemase inhibitor | Bacillus cereus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43660 | - |
x * 43660, sequence calculation | Bacillus cereus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine | Bacillus cereus | - |
D-alanine | - |
r | |
L-alanine | Bacillus cereus DSA 1 | - |
D-alanine | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus cereus | - |
motile strain isolated from gnocchi | - |
Bacillus cereus DSA 1 | - |
motile strain isolated from gnocchi | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spore | DSA 1 spores lack an intact exosporium | Bacillus cereus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine | - |
Bacillus cereus | D-alanine | - |
r | |
L-alanine | - |
Bacillus cereus DSA 1 | D-alanine | - |
r |
Subunits | Comment | Organism |
---|---|---|
? | x * 43660, sequence calculation | Bacillus cereus |
Synonyms | Comment | Organism |
---|---|---|
ALR | - |
Bacillus cereus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Bacillus cereus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
assay at | Bacillus cereus |
General Information | Comment | Organism |
---|---|---|
physiological function | involvement of alanine racemase in germination of Bacillus cereus spores lacking an intact exosporium. L-Alanine-mediated germination of food isolated Bacillus cereus DSA 1 spores, which lack an intact exosporium, is increased in the presence of D-cycloserine, an alanine racemase inhibitor, reflecting the activity of the Alr enzyme, capable of converting L-alanine to the germination inhibitor D-alanine, contribution of alanine racemase to the autoinhibition of Bacillus cereus spore germination | Bacillus cereus |