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Literature summary for 4.6.1.6 extracted from

  • Newton, R.P.; Salvage, B.J.; Hakeem, N.A.
    Cytidylate cyclase: development of assay and determination of kinetic properties of a cytidine 3,5-cyclic monophosphate-synthesizing enzyme (1990), Biochem. J., 265, 581-586.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.6

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.22
-
 CTP pH 7.4, 37°C Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+
-
 Rattus norvegicus
Mn2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CTP Rattus norvegicus
-
 3',5'-cyclic CMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
lung
-
 Rattus norvegicus
-
ovary
-
 Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-
stomach
-
 Rattus norvegicus
-
testis
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0012
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP
-
 Rattus norvegicus 3',5'-cyclic CMP + diphosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 7.5
-
 Rattus norvegicus
7.5
-
 liver enzyme Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
5.5 9.5 about 35% of activity maximum at pH 5.5, about 55% of activity maximum at pH 9.5 Rattus norvegicus