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Literature summary for 4.6.1.23 extracted from

  • Chan, Y.L.; Endo, Y.; Wool, I.G.
    The sequence of the nucleotides at the alpha-sarcin cleavage site in rat 28 S ribosomal ribonucleic acid (1983), J. Biol. Chem., 258, 12768-12770 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Aspergillus giganteus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Rattus norvegicus 28S rRNA containing guanosine-adenosine pair + H2O alpha-sarcin hydrolyzes a phosphodiester bond on the 3' side of a guanine residue 393 nucleotides from the 3' end. The alpha-sarcin domain is composed of a purine-rich sequence of 14 highly conserved nucleotides Aspergillus giganteus an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
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