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Literature summary for 4.6.1.23 extracted from

  • Tayyrov, A.; Azevedo, S.; Herzog, R.; Vogt, E.; Arzt, S.; Luethy, P.; Mueller, P.; Ruehl, M.; Hennicke, F.; Kuenzler, M.
    Heterologous production and functional characterization of ageritin, a novel type of ribotoxin highly expressed during fruiting of the edible mushroom Agrocybe aegerita (2019), Appl. Environ. Microbiol., 85, e01549 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Cyclocybe aegerita

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm sequence lacks a signal peptide for classical secretion Cyclocybe aegerita 5737
-

Organism

Organism UniProt Comment Textmining
Cyclocybe aegerita C0HLG3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rabbit 28S rRNA containing guanosine-adenosine pair + H2O
-
 Cyclocybe aegerita an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
 ?
rabbit ribosomes + H2O ribosomes isolated from reticulocyte lysate Cyclocybe aegerita ?
-
 ?

Synonyms

Synonyms Comment Organism
AGT1
-
 Cyclocybe aegerita

Expression

Organism Comment Expression
Cyclocybe aegerita expression is highly induced during fruiting up

General Information

General Information Comment Organism
physiological function ageritin heterologously expressed in Escherichia coli shows a strong toxicity against Aedes aegypti larvae yet not against nematodes. Entomotoxicity of ageritin is mediated by ribonucleolytic cleavage Cyclocybe aegerita