Literature summary for 4.6.1.23 extracted from

Alvarez-Garcia, E.; Garcia-Ortega, L.; Verdun, Y.; Bruix, M.; Martinez del Pozo, A.; Gavilanes, J.G.
Tyr-48, a conserved residue in ribotoxins, is involved in the RNA-degrading activity of alpha-sarcin (2006), Biol. Chem., 387, 535-541.

Search for more literature for 4.6.1.23

Protein Variants

Protein Variants	Comment	Organism
Y48F	mutant is produced in Escherichia coli and purified to homogeneity (ca. 3 mg/l of original bacterial culture)	Aspergillus giganteus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.04	-	ApA	wild-type	Aspergillus giganteus
0.043	-	ApA	Y48F mutant	Aspergillus giganteus

Organism

Organism	UniProt	Comment	Textmining
Aspergillus giganteus	P00655	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ApA + H2O	-	Aspergillus giganteus	3'-AMP + adenosine	-	?

Synonyms

Synonyms	Comment	Organism
alpha-sarcin	-	Aspergillus giganteus

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.00007	-	ApA	Y48F mutant	Aspergillus giganteus
0.0001	-	ApA	wild-type	Aspergillus giganteus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)