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Literature summary for 4.6.1.23 extracted from

  • Lacadena, J.; Martinez del Pozo, A.; Lacadena, V.; Martinez-Ruiz, A.; Mancheno, J.M.; Onaderra, M.; Gavilanes, J.G.
    The cytotoxin alpha-sarcin behaves as a cyclizing ribonuclease (1998), FEBS Lett., 424, 46-48.
    View publication on PubMed
Search for more literature for 4.6.1.23

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0036
-
 GpA pH 7.0, 25°C Aspergillus giganteus
0.04
-
 ApA pH 7.0, 25°C Aspergillus giganteus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
rRNA + H2O Aspergillus giganteus
-
 ?
-
 ?
rRNA + H2O Aspergillus giganteus MDH 18894
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus giganteus
-
 MDH 18894
-
Aspergillus giganteus
-
 filamentous fungus, mold
-
Aspergillus giganteus MDH 18894
-
 MDH 18894
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ApA + H2O
-
 Aspergillus giganteus 3'-AMP + adenosine
-
 ?
ApA + H2O
-
 Aspergillus giganteus MDH 18894 3'-AMP + adenosine
-
 ?
GpA + H2O hydrolysis of the 3'-5' phosphodiester bond of the substrate yields 2',3'-cyclic adenosine mononucleotide, this intermediate is converted into the corresponding 3'-monophosphate derivative as the final product of the reaction Aspergillus giganteus 3'-GMP
-
 ?
GpA + H2O hydrolysis of the 3'-5' phosphodiester bond of the substrate yields 2',3'-cyclic adenosine mononucleotide, this intermediate is converted into the corresponding 3'-monophosphate derivative as the final product of the reaction Aspergillus giganteus MDH 18894 3'-GMP
-
 ?
additional information acts as a cyclizing ribonuclease Aspergillus giganteus ?
-
 ?
additional information acts as a cyclizing ribonuclease Aspergillus giganteus MDH 18894 ?
-
 ?
rRNA + H2O
-
 Aspergillus giganteus ?
-
 ?
rRNA + H2O
-
 Aspergillus giganteus MDH 18894 ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.000009
-
 GpA pH 7.0, 25°C Aspergillus giganteus
0.0001
-
 ApA pH 7.0, 25°C Aspergillus giganteus