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Literature summary for 4.6.1.2 extracted from

  • Ghosh, A.; Stuehr, D.J.
    Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme (2012), Proc. Natl. Acad. Sci. USA, 109, 12998-13003.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Rattus norvegicus
-
3',5'-cyclic GMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
Rattus norvegicus 3',5'-cyclic GMP + diphosphate
-
?

Subunits

Subunits Comment Organism
heterodimer
-
Rattus norvegicus

Synonyms

Synonyms Comment Organism
sGC
-
Rattus norvegicus
soluble guanylyl cyclase
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
heme heat shock protein 90 is required to drive heme insertion into the enzyme and complete ist maturation Rattus norvegicus