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Literature summary for 4.6.1.2 extracted from

  • Usami, S.; Kishimoto, I.; Saito, Y.; Harada, M.; Kuwahara, K.; Nakagawa, Y.; Nakanishi, M.; Yasuno, S.; Kangawa, K.; Nakao, K.
    Association of CT dinucleotide repeat polymorphism in the 5-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese (2008), Hypertens. Res., 31, 89-96.
    View publication on PubMed
Search for more literature for 4.6.1.2

Application

Application Comment Organism
diagnostics CT and GA polymorphisms in the 5'-flanking region of the GC-A gene might be useful as susceptibility marker for hypertension Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
GC-A gene, genotyping of hypertensive and normotensive Japanese, association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the GC-A gene with essential hypertension in the Japanese, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information identification of CT and GA polymorphisms in the 5'-flanking region and the promoter region that acts synergistically to affect the GC-A promoter, transcription activity of genotypes, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Homo sapiens
-
 3',5'-cyclic GMP + diphosphate
-
 ?
additional information Homo sapiens association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase A gene with essential hypertension in the Japanese, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 hypertensive and normotensive Japanese
-

Source Tissue

Source Tissue Comment Organism Textmining
smooth muscle cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Homo sapiens 3',5'-cyclic GMP + diphosphate
-
 ?
additional information association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase A gene with essential hypertension in the Japanese, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GC-A
-
 Homo sapiens
guanylyl cyclase A
-
 Homo sapiens