Activating Compound | Comment | Organism | Structure |
---|---|---|---|
atrial natriuretic peptide | activation of isoforms GC-A and GC-B | Homo sapiens | |
atrial natriuretic peptide | activation of isoforms GC-A and GC-B | Rattus norvegicus | |
atrial natriuretic peptide | activation of isoforms GC-A and GC-B | Oryctolagus cuniculus | |
brain natriuretic peptide | activation of isoforms GC-A and GC-B | Homo sapiens | |
brain natriuretic peptide | activation of isoforms GC-A and GC-B | Rattus norvegicus | |
brain natriuretic peptide | activation of isoforms GC-A and GC-B | Oryctolagus cuniculus | |
C-type natriuretic peptide | activation of isoforms GC-A and GC-B | Homo sapiens | |
C-type natriuretic peptide | activation of isoforms GC-A and GC-B | Rattus norvegicus | |
C-type natriuretic peptide | activation of isoforms GC-A and GC-B | Oryctolagus cuniculus | |
guanylin | activation of isoform GC-C | Homo sapiens | |
guanylin | activation of isoform GC-C | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
membrane | - |
Oryctolagus cuniculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Homo sapiens | - |
3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | Rattus norvegicus | - |
3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | Oryctolagus cuniculus | - |
3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | brain natriuretic peptide stimulated membrane-bound GC | Rattus norvegicus | - |
gastrointestinal tract | atrial- and C-type natriuretic peptide stimulated membrane-bound GC | Rattus norvegicus | - |
kidney | C-type natriuretic peptide stimulated membrane-bound-GC | Rattus norvegicus | - |
lung | GC-A activity is detected on mucus secreting globlet cells, Clara cells and grat alveolar cells | Rattus norvegicus | - |
neurohypophysis | brain- and atrial natriuretic peptide stimulated membrane-bound GC | Rattus norvegicus | - |
peripheral nerve | - |
Rattus norvegicus | - |
placenta | - |
Homo sapiens | - |
platelet | atrial natriuretic peptide stimulated membrane-bound GC | Oryctolagus cuniculus | - |
sweat gland | atrial natriuretic peptide stimulated membrane-bound GC and guanylin-stimulated GC-C | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Homo sapiens | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | - |
Rattus norvegicus | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | - |
Oryctolagus cuniculus | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
membrane-bound GC | - |
Homo sapiens |
membrane-bound GC | - |
Rattus norvegicus |
membrane-bound GC | - |
Oryctolagus cuniculus |
membrane-bound guanylate cyclase | - |
Homo sapiens |
membrane-bound guanylate cyclase | - |
Rattus norvegicus |
membrane-bound guanylate cyclase | - |
Oryctolagus cuniculus |