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Literature summary for 4.6.1.16 extracted from

  • Thompson, L.D.; Daniels, C.J.
    A tRNA(Trp) intron endonuclease from Halobacterium volcanii. Unique substrate recognition properties (1988), J. Biol. Chem., 263, 17951-17959.
    View publication on PubMed
Search for more literature for 4.6.1.16

Activating Compound

Activating Compound Comment Organism Structure
spermidine required Haloferax volcanii

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Mg2+ or Ca2+ required Haloferax volcanii
Mg2+ required Haloferax volcanii
Mg2+ Mg2+ or Ca2+ required Haloferax volcanii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tRNA precursor Haloferax volcanii
-
 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?

Organism

Organism UniProt Comment Textmining
Haloferax volcanii
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Haloferax volcanii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tRNA precursor
-
 Haloferax volcanii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
tRNA precursor precise and accurate excision of the intron from halobacterial tRNATrp precursor Haloferax volcanii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
tRNA precursor specific for halobacterial tRNATrp substrates, does not remove the intron from a yeast pre-tRNAPhe substrate Haloferax volcanii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
tRNA precursor does not require intact mature tRNA structure in the substrate Haloferax volcanii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
tRNA precursor endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini Haloferax volcanii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?