Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | not stimulated by calcium, bicarbonate and forskolin | Mycobacterium avium |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Mycobacterium avium |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2',5'-dideoxy-3'-adenosine triphosphate | IC50 of about 730 nM | Mycobacterium avium | |
2'-deoxy-3'-adenosine monophosphate | IC50 of about 50 microM | Mycobacterium avium | |
NaCl | reduced enzyme activity in the presence of 500 mM NaCl | Mycobacterium avium | |
tyrphostin A25 | IC50 of about 36 microM | Mycobacterium avium |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | apparent Km for MnATP 0.393 mM | Mycobacterium avium |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | - |
Mycobacterium avium |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium avium | Q5UFR5 | - |
- |
Mycobacterium avium TN104 | Q5UFR5 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Mycobacterium avium |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
Vmax 212 nmol cAMP produced/min/mg protein | Mycobacterium avium |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Mycobacterium avium | cAMP + diphosphate | - |
? | |
ATP | - |
Mycobacterium avium TN104 | cAMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
adenylyl cyclase | - |
Mycobacterium avium |
Ma1120 | - |
Mycobacterium avium |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Mycobacterium avium |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Mycobacterium avium |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00073 | - |
IC50 of about 730 nM | Mycobacterium avium | 2',5'-dideoxy-3'-adenosine triphosphate | |
0.036 | - |
IC50 of about 36 microM | Mycobacterium avium | tyrphostin A25 | |
0.05 | - |
IC50 of about 50 microM | Mycobacterium avium | 2'-deoxy-3'-adenosine monophosphate |