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Literature summary for 4.6.1.1 extracted from
- Differential superactivation of adenylyl cyclase isozymes after chronic activation of the CB1 cannabinoid receptor (2000), Mol. Pharmacol., 57, 746-752.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | acute activation of cannabinoid receptor 1 leads to stimulation of isoenzymes AC II, AC IV and AC VII | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of isoenzymes ACI-ACVIII in COS cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | acute activation of cannabinoid receptor 1 leads to inhibition of isoenzymes ACI, AC III, AC VI and AC VIII | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP | Homo sapiens | - |
3',5'-cyclic AMP + diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP | - |
Homo sapiens | 3',5'-cyclic AMP + diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AC | - |
Homo sapiens |
| adenylyl cyclase | - |
Homo sapiens |
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