Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.4.1.4 extracted from

  • Krest, I.; Keusgen, M.
    Stabilization and pharmaceutical use of alliinase (1999), Pharmazie, 54, 289-293.
    View publication on PubMed

Application

Application Comment Organism
pharmacology allicin contributes to the prevention of stroke and arteriosclerosis. An acid resistant capsule is filled with pellets of alliin and alliinase. In the intestine, alliin and alliinase are dissolved and alicin is liberated Allium sativum

General Stability

General Stability Organism
cycled thawing and freezing leads to a loss in activity of about 40% for each cycle Allium sativum
the partially purified enzyme can be stabilized over several months by addition of sodium chloride, sucrose, and pyridoxal 5'-phosphate. The stabilized enzyme can be freeze-dried Allium sativum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-allyl-L-cysteine sulfoxide + H2O Allium sativum
-
2-propene-thioic acid + pyruvate + NH4+ + H+
-
?

Organism

Organism UniProt Comment Textmining
Allium sativum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Allium sativum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-allyl-L-cysteine sulfoxide + H2O
-
Allium sativum 2-propene-thioic acid + pyruvate + NH4+ + H+
-
?