Any feedback?
Literature summary for 4.4.1.20 extracted from
- Leukotriene C4 synthase homo-oligomers detected in living cells by bioluminescence resonance energy transfer (2003), Biochim. Biophys. Acta, 1633, 90-95.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| LTCS(1-115) | C-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(1-24) | C-terminally truncated protein, gives no bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(1-58) | C-terminally truncated protein, gives no bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(1-88) | C-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(114-150) | N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(23-115) | C- and N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(23-150) | N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(57-150) | N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
| LTCS(87-150) | N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
| nuclear membrane | - |
Homo sapiens | 31965 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 17000 | - |
x * 17000, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene C4 | Homo sapiens | - |
leukotriene A4 + glutathione | - |
r |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q16873 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 | - |
r | |
| leukotriene C4 | - |
Homo sapiens | leukotriene A4 + glutathione | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 17000, SDS-PAGE | Homo sapiens |
| More | forms homo-oligomers of LTCS fusion proteins with Renilla luciferase | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| leukotriene C4 synthase | - |
Homo sapiens |
| LTCS | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
