Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diethylcarbamazine | IC50: 0.05 mM | Homo sapiens | |
NEM | IC50: 0.02 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0056 | - |
leukotriene A4 | pH 7.4, 25°C | Homo sapiens | |
1.2 | - |
glutathione | pH 7.4, 25°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
U-937 cell | monocytic leukemia cell line | Homo sapiens | - |
U-937 cell | dimethyl sulfoxide-differentiated and undifferentiated | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000399 | - |
differentiated cells | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 + H2O | - |
? | |
leukotriene A4 + glutathione | - |
Rattus norvegicus | leukotriene C4 + H2O | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.02 | - |
IC50: 0.02 mM | Homo sapiens | NEM | |
0.05 | - |
IC50: 0.05 mM | Homo sapiens | diethylcarbamazine |