Activating Compound | Comment | Organism | Structure |
---|---|---|---|
alpha-keto-gamma-methiolbutyrate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
93000 | - |
enzyme from rat kidney mitochondrion, most of the activity is present in the low-molecular weight fraction, gel filtration | Rattus norvegicus |
200000 | - |
enzyme from rat kidney mitochondrion, some activity is present in the high-molecular weight fraction, gel filtration | Rattus norvegicus |
330000 | - |
enzyme from rat kidney cytosol, gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | cysteine S-conjugate beta-lyases catalyze beta-elimination reactions with cysteine S-conjugates that possess a good leaving group in the beta-position. The end products are aminoacrylate and a sulfur-containing fragment. The aminoacrylate tautomerizes and hydrolyzes to pyruvate and ammonia. | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-1,1,2,2-tetrafluoroethyl-L-cysteine + H2O | - |
Rattus norvegicus | ? + NH3 + pyruvate | - |
? | |
additional information | cysteine S-conjugate beta-lyases catalyze beta-elimination reactions with cysteine S-conjugates that possess a good leaving group in the beta-position. The end products are aminoacrylate and a sulfur-containing fragment. The aminoacrylate tautomerizes and hydrolyzes to pyruvate and ammonia. | Rattus norvegicus | ? | - |
? | |
RS-CH2-CH(NH3+)COO- + H2O | - |
Rattus norvegicus | RSH + NH3 + pyruvate | - |
? | |
S-1,2-dichlorovinyl-L-cysteine + H2O | - |
Rattus norvegicus | dichlorovinyl mercaptane + NH3 + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cysteine S-conjugate beta-lyase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | pyridoxal 5'-phosphate-containing enzyme | Rattus norvegicus |