Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.4.1.13 extracted from

  • Cooper, A.J.; Pinto, J.T.; Krasnikov, B.F.; Niatsetskaya, Z.V.; Han, Q.; Li, J.; Vauzour, D.; Spencer, J.P.
    Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase (2008), Arch. Biochem. Biophys., 474, 72-81.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.13

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-S-L-cysteinyldopamine slow beta-elimination reaction Homo sapiens pyruvate + ?
-
 ?
benzothiazolyl-L-cysteine
-
 Homo sapiens ?
-
 ?
beta-chloro-DL-alanine
-
 Homo sapiens ?
-
 ?
additional information beta-lyase reactions with S-(1,1,2,2-tetrafluoroethyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-cysteine, and Se-methyl-L-selenocysteine are more favorable than the GTK-catalyzed aminotransferase reactions with these amino acids Homo sapiens ?
-
 ?
additional information no reaction with 5-S-L-cysteinyl-L-DOPA Homo sapiens ?
-
 ?
RSH-CH2-CH(NH3+)COO- + H2O
-
 Homo sapiens RSH + NH3 + pyruvate
-
 ?
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
-
 Homo sapiens NH3 + pyruvate + 1,1,2,2-tetrafluoroethanethiol
-
 ?
S-(1,2-dichlorovinyl)-L-cysteine
-
 Homo sapiens ?
-
 ?
Se-methyl-L-selenocysteine
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
beta-lyase
-
 Homo sapiens
glutamine transaminase K exhibits broad specificity both as an aminotransferase and as a cysteine S-conjugate beta-lyase Homo sapiens
GTK
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Homo sapiens