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Literature summary for 4.4.1.13 extracted from

  • Commandeur, J.N.; Andreadou, I.; Rooseboom, M.; Out, M.; de Leur, L.J.; Groot, E.; Vermeulen, N.P.
    Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate beta-lyase/glutamine transaminase K (2000), J. Pharmacol. Exp. Ther., 294, 753-761.
    View publication on PubMed
Search for more literature for 4.4.1.13

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetic parameters for differentially substituted cysteine-S-conjugates and selenocysteine Se-conjugates Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47700
-
 x * 47700, MALDI-TOF Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-20°C, 50 mM Tris-HCl, pH 8.0, 2 years, no significant decrease in activity Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information kinetic analyses and comparison of beta-elimination reaction and transamination reaction for differentially substituted cysteine-S-conjugates and selenocysteine Se-conjugates Rattus norvegicus ?
-
 ?
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
-
 Rattus norvegicus ?
-
 ?
S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine
-
 Rattus norvegicus ?
-
 ?
Se-(4-methylbenzyl)-L-selenocysteine
-
 Rattus norvegicus ?
-
 ?
Se-(allyl)-L-selenocysteine
-
 Rattus norvegicus ?
-
 ?
Se-(isopropyl)-L-selenocysteine
-
 Rattus norvegicus ?
-
 ?
Se-(phenyl)-L-selenocysteine
-
 Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 47700, MALDI-TOF Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Rattus norvegicus