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Literature summary for 4.4.1.11 extracted from

  • Tanaka, H.; Esaki, N.; Soda, K.
    A versatile bacterial enzyme: L-methionine gamma-lyase (1985), Enzyme Microb. Technol., 7, 530-537.
No PubMed abstract available
Search for more literature for 4.4.1.11

Inhibitors

Inhibitors Comment Organism Structure
NaBH4
-
 Aeromonas sp.
NaBH4
-
 Pseudomonas putida

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Pseudomonas putida
additional information
-
 additional information
-
 Aeromonas sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41000
-
 4 * 41000, SDS-PAGE Aeromonas sp.
43000
-
 4 * 43000, SDS-PAGE Pseudomonas putida
149000
-
 gel filtration Aeromonas sp.
159000
-
-
 Pseudomonas putida
159000
-
 low-angle light-scattering method Aeromonas sp.
165000
-
 sedimentation equilibrium method Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-methionine Pseudomonas putida bacterial metabolism of methionine ?
-
 ?
L-methionine Aeromonas sp. bacterial metabolism of methionine ?
-
 ?

Organism

Organism UniProt Comment Textmining
Aeromonas sp.
-
-
-
Pseudomonas putida
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate mechanism Pseudomonas putida
a
L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate mechanism Aeromonas sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethionine
-
 Pseudomonas putida ?
-
 ?
ethionine
-
 Aeromonas sp. ?
-
 ?
L-cysteine
-
 Pseudomonas putida ?
-
 ?
L-cysteine
-
 Aeromonas sp. ?
-
 ?
L-methionine bacterial metabolism of methionine Pseudomonas putida ?
-
 ?
L-methionine bacterial metabolism of methionine Aeromonas sp. ?
-
 ?
additional information multicatalytic: alpha,gamma-elimination and gamma-replacement reactions of L-methionine and its analogs, alpha, beta-elimination and beta-replacement of L-cysteine and its analogs, deamination and gamma-addition of vinylglycine and deuterium labelling at alpha and beta position of L-methionine and other straight-chain L-amino acids Pseudomonas putida ?
-
 ?
additional information multicatalytic: alpha,gamma-elimination and gamma-replacement reactions of L-methionine and its analogs, alpha, beta-elimination and beta-replacement of L-cysteine and its analogs, deamination and gamma-addition of vinylglycine and deuterium labelling at alpha and beta position of L-methionine and other straight-chain L-amino acids Aeromonas sp. ?
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 43000, SDS-PAGE Pseudomonas putida
tetramer 4 * 41000, SDS-PAGE Aeromonas sp.

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate 4 mol per mol of enzyme Pseudomonas putida
pyridoxal 5'-phosphate 4 mol per mol of enzyme Aeromonas sp.