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Literature summary for 4.4.1.1 extracted from

  • Webb, G.D.; Lim, L.H.; Oh, V.M.; Yeo, S.B.; Cheong, Y.P.; Ali, M.Y.; El Oakley, R.; Lee, C.N.; Wong, P.S.; Caleb, M.G.; Salto-Tellez, M.; Bhatia, M.; Chan, E.S.; Taylor, E.A.; Moore, P.K.
    Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery (2008), J. Pharmacol. Exp. Ther., 324, 876-882.
    View publication on PubMed
Search for more literature for 4.4.1.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
DL-propargylglycine
-
 Homo sapiens
DL-propargylglycine
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39700
-
 the 44.5 kDa bands for variant 1 of CSE are detected in all arteries tested with Western blotting. CSE variant 2 is also detected at 39.7 kDa in a few arteries, but the band is not as intense and is not detected in most arteries Homo sapiens
44500
-
 the 44.5 kDa bands for variant 1 of CSE are detected in all arteries tested with Western blotting. CSE variant 2 is also detected at 39.7 kDa in a few arteries, but the band is not as intense and is not detected in most arteries Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P32929
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
artery
-
 Rattus norvegicus
-
artery
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cysteine + H2O
-
 Rattus norvegicus sulfide + NH3 + pyruvate
-
 ?
L-cysteine + H2O
-
 Homo sapiens sulfide + NH3 + pyruvate
-
 ?

Synonyms

Synonyms Comment Organism
CSE
-
 Rattus norvegicus
CSE
-
 Homo sapiens
cystathionine gamma-lyase
-
 Rattus norvegicus
cystathionine gamma-lyase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Rattus norvegicus
pyridoxal 5'-phosphate
-
 Homo sapiens