Cloned (Comment) | Organism |
---|---|
- |
Catharanthus roseus |
for expression in Escherichia coli | Rauvolfia serpentina |
Crystallization (Comment) | Organism |
---|---|
cocrystallized with inhibitor 6, the complete data are collected to 3.0 A resolution | Rauvolfia serpentina |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-[(tert-butoxycarbonyl)amino]propyl (3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-(2-oxoethyl)-3,4-dihydro-2H-pyran-5-carboxylate | - |
Catharanthus roseus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-alpha(S)-strictosidine + H2O | Catharanthus roseus | - |
tryptamine + secologanin | - |
? | |
3-alpha(S)-strictosidine + H2O | Rauvolfia serpentina | - |
tryptamine + secologanin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | - |
- |
- |
Rauvolfia serpentina | P68175 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Catharanthus roseus |
- |
Rauvolfia serpentina |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-alpha(S)-strictosidine + H2O | - |
Catharanthus roseus | tryptamine + secologanin | - |
? | |
3-alpha(S)-strictosidine + H2O | - |
Rauvolfia serpentina | tryptamine + secologanin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
strictosidine synthase | - |
Catharanthus roseus |
strictosidine synthase | - |
Rauvolfia serpentina |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
activity assay | Catharanthus roseus |
30 | - |
activity assay | Rauvolfia serpentina |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
activity assay | Catharanthus roseus |
7 | - |
activity assay | Rauvolfia serpentina |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000003 | - |
- |
Catharanthus roseus | 3-[(tert-butoxycarbonyl)amino]propyl (3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-(2-oxoethyl)-3,4-dihydro-2H-pyran-5-carboxylate |