Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.3.2.9 extracted from

  • Azumi, K.; Ikeda, Y.; Takeuchi, T.; Nomura, T.; Sabau, S.; Hamada, J.; Okada, F.; Hosokawa, M.; Yokosawa, H.
    Localization and characterization of gamma-glutamyl cyclotransferase in cancer cells (2009), Mol. Med. Rep., 2, 385-391.
    View publication on PubMed
Search for more literature for 4.3.2.9

Cloned(Commentary)

Cloned (Comment) Organism
an ERpP cDNA library is constructed from mRNAs derived from ERpP cells Rattus norvegicus
into the vector pGEX6P1 for expression in Escherichia coli BL21 cells, into the plasmids pCIneo-FLAG, pCIneo-T7 and pEGFP-C1, into the vector pGEM-T Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Rattus norvegicus 5737
-
cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(gamma-L-glutamyl)-L-amino acid Rattus norvegicus
-
 5-oxoproline + L-amino acid
-
 ?
(gamma-L-glutamyl)-L-amino acid Homo sapiens
-
 5-oxoproline + L-amino acid
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O75223
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
by affinity chromatography on glutathione-Sepharose 4B beads and subsequently by elution through digestion with PreScission protease Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
BM-314 cell
-
 Homo sapiens
-
brain
-
 Homo sapiens
-
breast cancer cell
-
 Homo sapiens
-
Caco-2 cell
-
 Homo sapiens
-
CHCY-1 cell
-
 Homo sapiens
-
Colo-320 cell
-
 Homo sapiens
-
colon
-
 Homo sapiens
-
ER-1 cell ER-1-24h, ER-1-1M cell produced Rattus norvegicus
-
ERpP cell
-
 Rattus norvegicus
-
HBL-100 cell
-
 Homo sapiens
-
heart
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
KM-12 cell
-
 Homo sapiens
-
leukocyte
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
lung
-
 Homo sapiens
-
lung cancer cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
MDA-MB-453 cell
-
 Homo sapiens
-
ovary cancer cell
-
 Homo sapiens
-
placenta
-
 Homo sapiens
-
RAJI cell
-
 Homo sapiens
-
rectal cancer cell
-
 Homo sapiens
-
skeletal muscle
-
 Homo sapiens
-
small intestine
-
 Homo sapiens
-
spleen
-
 Homo sapiens
-
stomach cancer cell
-
 Homo sapiens
-
SW-480 cell
-
 Homo sapiens
-
thymus
-
 Homo sapiens
-
uterine cancer cell
-
 Homo sapiens
-
WiDr cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(gamma-L-glutamyl)-L-amino acid
-
 Rattus norvegicus 5-oxoproline + L-amino acid
-
 ?
(gamma-L-glutamyl)-L-amino acid
-
 Homo sapiens 5-oxoproline + L-amino acid
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Rattus norvegicus
homodimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
gamma-glutamyl cyclotransferase
-
 Rattus norvegicus
gamma-glutamyl cyclotransferase
-
 Homo sapiens
GGCT
-
 Rattus norvegicus
GGCT
-
 Homo sapiens
protein C7orf24
-
 Rattus norvegicus
protein C7orf24
-
 Homo sapiens