BRENDA - Enzyme Database
show all sequences of 4.3.2.2

Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs

Stuer-Lauridsen, B.; Nygaard, P.; J. Bacteriol. 180, 457-463 (1998)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Halobacterium salinarum
-
-
-
Haloferax volcanii
-
-
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
20
-
crude cell extract, presence of 1 M KCl, pH 7.5, temperature not specified in the publication
Haloferax volcanii
40
-
crude cell extract, presence of 1 M KCl, pH 7.5, temperature not specified in the publication
Halobacterium salinarum
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenylosuccinate
-
734059
Halobacterium salinarum
adenosine monophosphate + fumarate
-
-
-
?
adenylosuccinate
-
734059
Haloferax volcanii
adenosine monophosphate + fumarate
-
-
-
?
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
20
-
crude cell extract, presence of 1 M KCl, pH 7.5, temperature not specified in the publication
Haloferax volcanii
40
-
crude cell extract, presence of 1 M KCl, pH 7.5, temperature not specified in the publication
Halobacterium salinarum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenylosuccinate
-
734059
Halobacterium salinarum
adenosine monophosphate + fumarate
-
-
-
?
adenylosuccinate
-
734059
Haloferax volcanii
adenosine monophosphate + fumarate
-
-
-
?
General Information
General Information
Commentary
Organism
metabolism
comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels
Halobacterium salinarum
metabolism
comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels
Haloferax volcanii
General Information (protein specific)
General Information
Commentary
Organism
metabolism
comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels
Halobacterium salinarum
metabolism
comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels
Haloferax volcanii
Other publictions for EC 4.3.2.2
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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6
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729218
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Homo sapiens
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51
6701-6713
2012
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714232
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Homo sapiens
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2011
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1
1
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4
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716175
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Ctenopharyngodon idella
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38
2059-2065
2011
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1
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730526
Bierau
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30
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2011
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2
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708663
Zikanova
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Homo sapiens
Hum. Mutat.
31
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2010
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1
-
15
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2
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2
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1
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15
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2
1
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1
1
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709392
Chen
Adenylosuccinate lyase deficie ...
Homo sapiens
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33
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2010
-
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2
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709768
Chauhan
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Pantoea agglomerans
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50
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2010
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710076
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56
367-378
2010
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1
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1
1
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710131
Henneke
In vivo proton MR spectroscopy ...
Homo sapiens
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23
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2010
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713618
Fyfe
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Acta Crystallogr. Sect. D
66
881-888
2010
-
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692168
Gitiaux
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2009
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706979
Kozlov
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Acta Crystallogr. Sect. F
65
857-861
2009
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707497
Ariyananda
Biochemical and biophysical an ...
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5291-5302
2009
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1
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5
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5
2
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2
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1
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708545
Mierzewska
Severe encephalopathy with bra ...
Homo sapiens
Folia Neuropathol.
47
314-320
2009
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1
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690934
De Zoysa Ariyananda
Evaluation of types of interac ...
Bacillus subtilis
Biochemistry
47
2923-2934
2008
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1
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7
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2
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691116
Bulusu
Elucidation of the substrate s ...
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Biochim. Biophys. Acta
1794
642-654
2008
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4
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1
1
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693982
Lopez
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71
657-663
2008
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694197
Jurecka
Clinical, biochemical and mole ...
Homo sapiens
Mol. Genet. Metab.
94
435-442
2008
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1
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8
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2
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2
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695003
Sivendran
Effect of a new non-cleavable ...
Bacillus subtilis, Homo sapiens
Protein Sci.
17
1162-1174
2008
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13
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2
3
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9
6
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13
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9
6
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8
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699380
Jurecka
D-Ribose therapy in four Polis ...
Homo sapiens
J. Inherit. Metab. Dis.
31
S329-332
2008
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34458
Carter
The preparation and properties ...
Saccharomyces cerevisiae
J. Biol. Chem.
222
17-30
1956
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