General Stability | Organism |
---|---|
repeated freezing and thawing does not appreciably alter the activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
argininosuccinate | - |
Homo sapiens | |
3 | - |
Arg | - |
Homo sapiens | |
5.3 | - |
fumarate | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49000 | - |
4 * 49000, SDS-PAGE | Homo sapiens |
187000 | - |
equilibrium sedimentation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
8 | - |
formation of argininosuccinate | Homo sapiens |
10.3 | - |
cleavage of argininosuccinate | Homo sapiens |
Storage Stability | Organism |
---|---|
frozen in 0.1 M potassium phosphate, pH 7.0, stable | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
argininosuccinate | - |
Homo sapiens | fumarate + L-Arg | - |
r | |
fumarate + L-Arg | - |
Homo sapiens | argininosuccinate | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 49000, SDS-PAGE | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | 7.2 | formation of argininosuccinate | Homo sapiens |
7.5 | - |
formation of argininosuccinate | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
7 | - |
at 4°C and at 25°C, 8 h, stable | Homo sapiens |
8.2 | - |
25°C, about 40% loss of activity after 8 h | Homo sapiens |
8.2 | - |
4°C, about 60% loss of activity after 4 h | Homo sapiens |