Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(6S)-5,6,7,8-tetrahydropteroylpolyglutamate | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0012 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylhexaglutamate | - |
Sus scrofa | |
0.002 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylpentaglutamate | - |
Sus scrofa | |
0.0021 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylheptaglutamate | - |
Sus scrofa | |
0.0029 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroyltetraglutamate | - |
Sus scrofa | |
0.021 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroyltriglutamate | - |
Sus scrofa | |
0.149 | - |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylglutamate | - |
Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-formiminotetrahydrofolate | Sus scrofa | - |
? | - |
? | |
additional information | Sus scrofa | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | ? | - |
? | |
additional information | Sus scrofa | direct transfer of the formimino intermediates between the active sites of the formiminotransferase-cyclodeaminase enzyme complex, with complete "channeling" of the pentaglutamate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(6S)-5-formimino-5,6,7,8-tetrahydropteroylglutamate | - |
Sus scrofa | ? | - |
? | |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylheptaglutamate | - |
Sus scrofa | ? | - |
? | |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylhexaglutamate | - |
Sus scrofa | ? | - |
? | |
(6S)-5-formimino-5,6,7,8-tetrahydropteroylpentaglutamate | - |
Sus scrofa | ? | - |
? | |
(6S)-5-formimino-5,6,7,8-tetrahydropteroyltetraglutamate | - |
Sus scrofa | ? | - |
? | |
(6S)-5-formimino-5,6,7,8-tetrahydropteroyltriglutamate | - |
Sus scrofa | ? | - |
? | |
5-formiminotetrahydrofolate | - |
Sus scrofa | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
5-formiminotetrahydrofolate | - |
Sus scrofa | ? | - |
? | |
additional information | - |
Sus scrofa | ? | - |
? | |
additional information | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | Sus scrofa | ? | - |
? | |
additional information | direct transfer of the formimino intermediates between the active sites of the formiminotransferase-cyclodeaminase enzyme complex, with complete "channeling" of the pentaglutamate | Sus scrofa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
octamer | formiminotransferase-cyclodeaminase enzyme complex is composed of eight subunits arranged in a planar ring | Sus scrofa |