Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.3.1.24 extracted from

  • Gubica, T.; Pe?ka, A.; Pa?ka, K.; Temeriusz, A.; Ka?ska, M.
    The influence of cyclomaltooligosaccharides (cyclodextrins) on the enzymatic decomposition of L-phenylalanine catalyzed by phenylalanine ammonia-lyase (2011), Carbohydr. Res., 346, 1855-1859.
    View publication on PubMed
Search for more literature for 4.3.1.24

Inhibitors

Inhibitors Comment Organism Structure
cyclomaltoheptaose
-
 Rhodotorula glutinis
cyclomaltohexaose
-
 Rhodotorula glutinis
heptakis(2,3,6-tri-O-methyl)cyclomaltoheptaose
-
 Rhodotorula glutinis
heptakis(2,3-di-O-methyl)cyclomaltoheptaose competitive and noncompetitive inhibition Rhodotorula glutinis
hexakis(2,3,6-tri-O-methyl)cyclomaltohexaose
-
 Rhodotorula glutinis
hexakis(2,3-di-O-methyl)cyclomaltohexaose competitive and noncompetitive inhibition, activation at 2 and 3 mM Rhodotorula glutinis
additional information cyclodextrins show mixed inhibition, both competitive and noncompetitive, but they also act as activators for selected concentrations. The inhibitory effect of cyclodextrins is connected with the decrease of substrate concentration and unfavourable influence on the flexibility of the enzyme molecules. On the other hand, the activating effect is connected with the decrease of product concentration i.e. the product is an inhibitor of the enzymatic reaction under investigation Rhodotorula glutinis

Organism

Organism UniProt Comment Textmining
Rhodotorula glutinis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Rhodotorula glutinis
-