Crystallization (Comment) | Organism |
---|---|
homology modeling of structure. The active state of enzyme is a Tyr110-loop-in conformation and opening-closing the entrance to the active site may happen by a breathing motion of this loop. Comparison with strucutural models of Photorhabdus luminescens and Streptomyces maritimus enzymes | Petroselinum crispum |
molecular dynamics studies. The Tyr61-loop-in model is conformationally stable and assumed to be the active form. Deletion of the C-terminal multi-helix domain results in a significantly more rigid Tyr-loop-in structure. Comparison with strucutural models of Petroselinum crispum and Photorhabdus luminescens enzymes | Streptomyces maritimus |
molecular dynamics studies. The Tyr61-loop-in model is conformationally stable and assumed to be the active form. Deletion of the C-terminal multi-helix domain results in a significantly more rigid Tyr-loop-in structure. Comparison with strucutural models of Petroselinum crispum and Streptomyces maritimus enzymes | Photorhabdus luminescens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | a Tyr10-loop-in conformation of the enzyme structure is constructed by partial homology modeling, and the static and dynamic behavior of the loop-in/loop-out structures are compared | Petroselinum crispum |
additional information | building of Tyr-loop-in/loop-out model structure lacking the C-terminal domain | Photorhabdus luminescens |
additional information | building of Tyr-loop-in/loop-out model structure lacking the C-terminal domain | Streptomyces maritimus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Petroselinum crispum | P24481 | - |
- |
Photorhabdus luminescens | - |
- |
- |
Streptomyces maritimus | - |
- |
- |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
3,5-dihydro-5-methylidene-4H-imidazol-4-one | MIO cofactor | Photorhabdus luminescens | |
3,5-dihydro-5-methylidene-4H-imidazol-4-one | MIO cofactor | Streptomyces maritimus | |
3,5-dihydro-5-methylidene-4H-imidazol-4-one | MIO cofactor | Petroselinum crispum |