Cloned (Comment) | Organism |
---|---|
expression in Brevibacterium flavum | Escherichia coli |
expression in Corynebacterium glutamicum | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ile | native enzyme is totally inhibited by 15 mM Ile, the heterologous catabolic enzyme from E. coli retains 60% of its original activity even in presence of 200 mM Ile | Corynebacterium glutamicum | |
Ile | biodegradative enzyme is feedback-resistant | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Thr | Escherichia coli | first reaction of the Ile pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | - |
- |
- |
Escherichia coli | - |
biodegradative threonine dehydratase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Thr | first reaction of the Ile pathway | Escherichia coli | ? | - |
? | |
L-threonine | - |
Escherichia coli | 2-oxobutanoate + NH3 | - |
? | |
L-threonine | - |
Corynebacterium glutamicum | 2-oxobutanoate + NH3 | - |
? |