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Literature summary for 4.3.1.15 extracted from

  • Ernst, D.C.; Anderson, M.E.; Downs, D.M.
    L-2,3-diaminopropionate generates diverse metabolic stresses in Salmonella enterica (2016), Mol. Microbiol., 101, 210-223 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-diaminopropanoate + H2O Salmonella enterica specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress pyruvate + 2 NH3
-
?
2,3-diaminopropanoate + H2O Salmonella enterica DM14828 specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress pyruvate + 2 NH3
-
?

Organism

Organism UniProt Comment Textmining
Salmonella enterica P40817 the strain is generated from Salmonella enterica serovar typhimurium LT2
-
Salmonella enterica DM14828 P40817 the strain is generated from Salmonella enterica serovar typhimurium LT2
-

Purification (Commentary)

Purification (Comment) Organism
-
Salmonella enterica

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.9
-
pH 8.0, 22°C Salmonella enterica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-diaminopropanoate + H2O specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress Salmonella enterica pyruvate + 2 NH3
-
?
2,3-diaminopropanoate + H2O diaminopropionate ammonia-lyase-dependent degradation of 2,3-diaminopropanoate to pyruvate proceeds through an unbound 2-aminoacrylate intermediate Salmonella enterica pyruvate + 2 NH3
-
?
2,3-diaminopropanoate + H2O specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress Salmonella enterica DM14828 pyruvate + 2 NH3
-
?
2,3-diaminopropanoate + H2O diaminopropionate ammonia-lyase-dependent degradation of 2,3-diaminopropanoate to pyruvate proceeds through an unbound 2-aminoacrylate intermediate Salmonella enterica DM14828 pyruvate + 2 NH3
-
?

Synonyms

Synonyms Comment Organism
DpaL
-
Salmonella enterica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
assay at Salmonella enterica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Salmonella enterica

Expression

Organism Comment Expression
Salmonella enterica expression of dpaL and protein production are specifically induced in Salmonella enterica when exposed to 2,3-diaminopropanoate up

General Information

General Information Comment Organism
metabolism specific role for the enzyme in degrading 2,3-diaminopropanoate to avoid metabolic stress Salmonella enterica