Literature summary for 4.2.99.18 extracted from

Manvilla, B.A.; Pozharski, E.; Toth, E.A.; Drohat, A.C.
Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor (2013), Acta Crystallogr. Sect. D, 69, 2555-2562.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
to 1.92 A resolution with a single Mg2+ ion in the active site. The structure reveals ideal octahedral coordination of Mg2+ via two carboxylate groups and four water molecules. One residue that coordinates Mg2+ directly and two that bind inner-sphere water molecules are strictly conserved in the DNase I superfamily	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P27695	-	-

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Release 2023.1 (January 2023)