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Literature summary for 4.2.99.18 extracted from

  • Roberts, S.A.; Strande, N.; Burkhalter, M.D.; Strom, C.; Havener, J.M.; Hasty, P.; Ramsden, D.A.
    Ku is a 5-dRP/AP lyase that excises nucleotide damage near broken ends (2010), Nature, 464, 1214-1217.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.99.18

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA 5'-deoxyribose-5-phosphate and apurinic/apyrimidinic sites are excised with half-lives of 2.7 and 7.0 min, respectively Homo sapiens fragments of DNA
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 ?

Synonyms

Synonyms Comment Organism
AP lyase
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 Homo sapiens
apurinic/apyrimidinic site lyase
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 Homo sapiens
More Ku is a NHEJ factors with effective 5'-deoxyribose-5-phosphate lyase/apurinic/apyrimidinic site lyase activities Homo sapiens